Predictive Titration: Use data to suggest when a patient is ready for a maintenance phase
Additionally, by reducing cravings across substances, GLP-1s have the potential to reduce substance substitution by patients after a successful cessation
It not only enhances insulin production and release, but also decreases glucagon secretion, increases glucose uptake and glycogen synthesis in peripheral tissues, delays gastric emptying, and increases satiety
doi:10.1111/bph.15638 **" Cost of weight-loss drug Mounjaro could rise significantly (BBC) Acknowledgements : Id like to thank Sebastian Furness for his excellent article on the history of GLP-1 in The Conversation titled- The rise of Ozempic: how surprise discoveries and lizard venom led to a new class of weight-loss drugs This review was also extremely helpful: Zheng Z, Zong Y, Ma Y, et al
Oral dosing (500 mcg to 1 mg in capsules) targets gut-related conditions: IBS, leaky gut, NSAID-induced gastric damage
If the brain feels unsafe, it doesnt process GLP-1 or PYY correctly, leading to a frantic search for food to soothe the system