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Further evidence comes from a post hoc analysis of the SURPASS programme of RCTs, which examined the efficacy of subcutaneous tirzepatidea dual GLP-1 RA and glucose-dependent insulinotropic polypeptide receptor agonistin doses of 5, 10, and 15 mg on various metabolic outcomes [66]

MMNST, first recorded by Millar in 1932 [3], most frequently arises from the region of spinal or autonomic nerves near the midline [1]

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95% CI, 0.53-0.69), though there was no statistically significant difference between the groups in the risk of MACE (HR, 1.10