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Accounting for a dropout rate of 15%, a total of 35 patients would need to be recruited in order to have 29 evaluable patients

Congressional Budget Office

It is not suitable for use during pregnancy, while planning to become pregnant, or while breastfeeding

Under a simulation model, even a narrow expansion of coverage for GLP-1s comes at a cost because the prices are so high

Semaglutide remains valuable for patients who tolerate it well, patients with specific cost considerations, or patients who need a longer established safety record

Regardless of the method, remember that these medications are designed to support a healthy lifestyle, not replace it