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Originally developed to manage blood sugar levels in diabetic patients, GLP-1 medications have gained massive popularity for their effectiveness in promoting sustained weight loss

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Statements Author contributions ZJ: Writing original draft

Some users report mild fatigue or drowsiness, particularly during the first few days of use

CONCLUSION: Peripheral GLP-1 decreased DIT and carbohydrate oxidation, probably secondary to a delayed absorption of nutrients, since substrate and hormone concentrations in plasma were suppressed during GLP-1 infusion

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