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On the other hand, such solvation anomalies are not expected to persist across more than one functional group, hence solvent-to-solvent correlation for p K a values across functional groups is rather poor (Tables 4, 5, 6, 7, 8, 9)

Enayati AA, Ranson H, Hemingway J

We define microdosing as any dose below the lowest commercially available starting dose

doi: 10.1172/JCI75456

[5] Cardiac conduction abnormalities

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