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Table A : GLP-1RAs versus other glucose-lowering agents: key specific features that impact treatment choice Given that there are few head-to-head studies comparing glucose-lowering effects between different drug classes, and the difficulty involved in performing cross-study comparisons due to different patient characteristics and baseline HbA 1c levels, there is widespread consensus that GLP-1RAs are more efficacious at lowering blood glucose than either DPP-IVs or SGLT-2 inhibitors

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Zhu, P., Oe, T

PCOS is mainly characterized by ovarian granulosa cell dysfunction (47)

Mechanistically, TMAO may promote autophagy-dependent cell death in human renal proximal tubular epithelial cells by activating the PERK/ROS pathway, thereby aggravating calcium oxalate crystal deposition and kidney injury

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