That is a genetic-knockdown study in mice, not a drug trial: it tells you the target is real and metabolically meaningful in an animal model, but it does not test a drug, a dose, or a route
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NNMTi can promote myoblast differentiation in vitro and enhance the fusion and regeneration capacity of muscle stem cells in aged mice
What none of them has, alone or blended, is a completed human trial, so the blend belongs firmly in the research-and-hypothesis column rather than the proven-protocol one
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These drugs were promising early on, but many were abandoned for either failing to show clear benefits or for allegedly causing severe side effects