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Additionally, this is accompanied by an increase in whole-body EE, suggesting that the fatty acids are preferentially utilized as metabolic fuel rather than stored ectopically or released to blood to induce hyperlipidemia conditions

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39 ASCT1 and ASCT2, which have mainly been studied in the context of glutamine dependence, are expressed at high levels in different cancer types, 40,41,42 prompting these transporters to be considered putative therapeutic targets in cancer, with different inhibitors currently under investigation

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