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Together, these results suggest that sleep and sleep deprivation bi-directionally can impact the molecular signalling pathways that regulate synaptic strength and control brain plasticity, supporting the hypothesis of a direct relation between cortical plasticity and sleep regulation ( Figure 4 )

It would be interesting to unravel the sleep-related mechanisms regulated by VitB12 in future laboratory experiments

Eur Respir J 2022, 60

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Current consensus definition: Prevalence, etiology, and consequences