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4.3.1 Ferroptosis: context-dependent relevance in neuroprotection and cancer Ferroptosis is a regulated form of cell death driven by iron-dependent lipid peroxidation, and its modulation can have different implications depending on the disease context

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Los estudios en humanos indican que tomar acetil-L-carnitina diariamente ayuda a revertir la disminucin de la funcin cerebral asociada con el Alzheimer y otras enfermedades cerebrales

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Acetoacetate (A) is produced primarily by liver mitochondria where -hydroxybutyrate dehydrogenase is highly expressed, and maintains a ratio of -hydroxybutyrate () to A of about 2, reflective of the mitochondrial NADH to NAD ratio