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Here, we used HDOCK to perform rigid-body docking calculations to predict the preferred binding interactions between the ApoC-II peptide (aa 5678) and the N-terminal Angptl4 fragment with LPL (73)

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The effect on stroke is remarkable (and was significant in the trials of both semaglutide and dulaglutide), amounting to an 18% risk reduction, also because the other class of new antidiabetic agents with cardiovascular benefits, the SGLT2-inhibitors, show no a similar effect on stroke (but do have a significant effect on heart failure) [24]

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The city pushed for the change last week, arguing it faces steep increases in its health care costs driven, in part, by a spike in city workers using GLP-1 drugs