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Association and dissociation rate constants were calculated using the kinetics of competitive binding algorithm in GraphPad Prism 43

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10.1016/j.biopsych.2015.04.005 67 MandalP

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At the end of treatment, the mean changes from baseline HbA1c were 2.4% and 1.6% in the 2.510.0 mg and 2.515.0 mg treatment groups, respectively