To sum up, the direct effects of GLP-1 (736) in the myocardium, combined with other actions of the peptide on the cardiovascular system (reviewed in 2124), may explain the beneficial effects of incretin-based therapies in cardiac structure and function, regardless of the presence or absence of T2DM (Fig
This includes resveratrol, curcumin, quercetin, baicalein, berberine and epigallocatechin gallate (EGCG), which have demonstrated pleiotropic neuroprotective effects by mitigating oxidative and inflammatory cascades, improving mitochondrial biogenesis, preventing proteostasis imbalance, and/or blocking -synuclein aggregation
It promotes nutrient partitioning without blocking fat oxidation
For patients who want to understand what good clinical oversight of GLP-1 treatment looks like in practice, including what lab work and monitoring to expect, the article on what lab tests to expect while on GLP-1 medications provides a useful reference
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