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While the liver was previously thought to be the main target of metformins glucose-lowering effects, recent evidence suggests that other parts of the body, such as the gastrointestinal tract, also play a role in its overall clinical advantages

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doi: 10.1002/acn3.682 14 UrsiniFMaiorinoMValenteMFerriLGregolinC

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Several mechanisms may account for the ability of this extract to nutritionally support the pancreas and, when used as part of the diet, to maintain healthy glucose metabolism