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For instance, animal models have shown that GLP-1RAs administration reduces anxiety-like behaviors, potentially via neuromodulatory actions in brain regions such as the amygdala

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Presence in Blood: It is not naturally occurring in significant amounts in the blood

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The following adverse reactions are also discussed elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice