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Currently, ALRN-6924 is being studied in several clinical trials (Table 3)

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A.AdamowiczA.TrafikowskaU.TrafikowskaA.ManitiusJ.NartowiczE.2001aSelenium and glutathione levels, and glutathione peroxidase activities in blood components of uremic patients on hemodialysis supplemented with selenium and treated with erythropoietin.15201208

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However, these beneficial effects are antagonized by pro-inflammatory adipokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6), which inhibit adiponectins activity