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However, the initial intent was never to use these molecules for cosmetic or aesthetic purposes

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While both substances may have similar effects on muscle growth, IGF-1 works by promoting cell proliferation, which is a biological process distinct from the actions of anabolic steroids

Nat Rev Chem 6 , 451469 (2022)

The answer is probably both direct and indirect, Habegger said

The effect of immediate release and extended release metformin on A1c levels is similar (55)