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Cashen DV, Parisien RC, Raskin K, Hornicek FJ, Gebhardt MC, Mankin HJ

The following story is a fictional educational example inspired by situations commonly discussed during medical weight loss consultations

Understanding bariatric surgery The term bariatric surgery refers to various weight loss procedures for people who are obese and havent been able to successfully lose weight (and keep it off) with diet and exercise alone

Secretion of Exe4 peptide via gene knock-in in Hepa1-6 cells To achieve sustained Exe4 secretion, we targeted the Albumin ( Alb ) locus due to its hepatocyte-specific high expression levels, ensuring robust expression of the integrated scExe4 gene 9,33,34

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Medication is prescribed at provider discretion and is one possible component of a larger protocol