doi: 10.3389/fimmu.2023.1136146
Recent studies have suggested that in cancer cells with elevated cytosolic NADH levels, the malate-aspartate shuttle (MAS) actively takes up NADH to produce ATP in mitochondria through the electron transport chain 142
Description GLP-3 RT (Triple GIP/GLP-1/Glucagon Receptor Agonist) Overview GLP-3 RT designates the class of investigational unimolecular triple hormone receptor agonists that simultaneously activate three distinct G protein-coupled receptors: the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR)
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