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Morning vs Night: What the Comparative Data Actually Shows A 2019 study comparing GH secretagogue timing in healthy adults found that nocturnal administration (defined as within 60 minutes of sleep onset) produced mean peak GH levels of 18.4 ng/mL, compared to 7.2 ng/mL for morning administration (within 30 minutes of waking)

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However, supplements may be appropriate for some but not all and can interact with other medicines a person might be using

This starting phase establishes tolerance and allows your prescriber to assess how your body responds before advancing to higher maintenance doses