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During the last 2 weeks of the titration periods in those 12 participants, semaglutide led to a higher time in range by 4.3 percentage points (5.5, P = 0.02), lower insulin usage by 12.2 U [16.2, 5.4] ( P = 0.008) and lower carbohydrate intake by 50 g (35

The biologically active forms of GLP-1 are rapidly degraded by DPP-4, resulting in the production of inactive forms of GLP-1 (GLP-1 937 and GLP-1 936 ) [11]

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In this case, multiple imputation was based on data from participants in the same treatment arm