Retatrutide is a weekly injection that is slightly more sophisticated than other GLP-1 drugs because it is a triple agonist. Unlike current drugs (Zepbound, Ozempic-type medications) that target one or two hormone pathways, retatrutide activates three hormone receptors (GIP, GLP-1, and glucagon) at once
Weight loss on its own can change muscle, bone and more
For patients who are unsure if GLP-1s are right for them, that lack of flexibility can make Hims feel like a gamble
We also reported that semaglutide and liraglutide (other selective GLP-1 agonists) augmented FOC in HAP (Neumann et al
Subcutaneous or oral formulations bind to GLP-1 receptors in the hypothalamus and throughout the gut, triggering satiety signals and reducing caloric intake
Insulin Resistance Insulin resistance affects approximately one in three adults and is frequently invisible for years