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We know metformin changes how you absorb macronutrients, particularly carbohydrates, but possibly fats and proteins, too. Other benefits of metformin include that it is safe, adds King

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Some users have complained of side effects such as nausea and other gastro-intestinal distress and regaining weight once they stopped using the drugs

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Studies** have shown that even in successful diets more than half of the weight lost is regained within two years, and by five years, over 80% of lost weight is regained