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Tirzepatide also acts on the GIP receptor, potentially providing greater benefits for blood sugar control and weight reduction compared to Ozempic

Its dual-receptor mechanism has generated significant academic interest, with research examining its distinct signalling properties compared to single-receptor GLP-1 agonists in pancreatic, adipose, and hypothalamic tissue contexts

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Men already on TRT may require a structured transition plan

DOI: Published online: February 24, 2021 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Corresponding author: Young Min Cho