Takahashi H, Chiu H-C, Bandera CA, Behbakht K, Liu PC, Couch FJ, Weber BL, LiVolsi VA, Furusato M, Rebane BA, Cardonick A, Benjamin I, Morgan MA, King SA, Mikuta JJ, Rubin SC, Boyd J
Why Im cautious: The human efficacy story is not in the same league as GLP-1 evidence
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doi: 10.1001/archinte.144.5.994
Via the catalytic activity of a broad superfamily of phase II detoxification enzymes, the Glutathione STransferases (GSTs), glutathione is covalently conjugated to electrophilic xenobiotics and endogenous reactive intermediates
Materials and methods: This review systematically evaluated the role of ferroptosis in ocular diseases using a predefined search strategy