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Therefore, individuals with conditions like Wilsons disease or active cancer should avoid all forms of GHK-Cu.

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GHK-Cu exerts its effects primarily through gene expression modulation, influencing approximately 31% of the human genome by upregulating genes involved in antioxidant responses, DNA repair, protein metabolism, and cellular growth while downregulating inflammatory mediators, fibrinogen synthesis, and pathological processes including cancer metastasis

First, most natural small molecules present low bioavailability problems [254], so further research on delivery systems and formulations for these drugs is needed