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and overexpression of STIM1 selectively in astrocytes fully recovers astrocyte Ca 2+ activity and synaptic plasticity in this model

L-asparaginase can deplete plasma Gln and is widely utilized as an adjuvant therapy in lymphoma (106)

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As expected, strains W303-1b/FG, W303-1b/FP and W303-1b/FGP yielded 206.70, 190.57 and 216.50 mg/L of GSH in shake flask cultures, indicating that introduction of a second pathway could enhance the synthetic capacity of GSH

Its deficiency causes oxidative stress that not only promotes the oxidation of proteins and deoxyribonucleic acid (DNA) but also leads to insulin resistance, dyslipidemia, inflammation, and metabolic alterations, which expose to high risk for cardiometabolic disorders due to cardiovascular and degenerative diseases especially when associated with aging

CJC-1295 is also a GHRH