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They are listed as controlled substances by the Drug Enforcement Administration (DEA) due to their potential for abuse, specifically a schedule IV listing for phentermine and a more concerning schedule II listing for Adderall

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The incretin effect is significantly blunted in type 2 diabetes mellitus (T2DM) and restoration of this incretin signalling could be effective as a treatment strategy for diabetes, obesity and metabolic dysfunctions [5, 6]

Thyroid Issues: The drug carries a black box warning for thyroid C-cell tumors in rodents, leading to human concerns about thyroid cancer, especially over extended use

Telogen effluvium is a common type of sudden hair loss that typically results from stress or shock

Published efficacy data for patches remain limited and preliminary