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I think it comes down to cost and tolerability

The products were being sold via the company's website

Continuing therapy while optimizing your dose addresses this differently

Tanshinone IIA loaded bioactive nanoemulsion for alleviation of lipopolysaccharide induced acute lung injury via inhibition of endothelial glycocalyx shedding

CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha

Less Common but Serious Side Effects: Hypoglycemia (Low Blood Sugar) : Especially when used with other diabetes medications like insulin or sulfonylureas