This is because it is approved for weight loss and the higher doses may not be suitable for type 2 diabetes
The safer comparison asks what is approved, what evidence is mature, what risks apply, and what monitoring a clinician can provide
This paper describes the ability of an oral peptide delivery formulation, Axcess, to enhance uptake of GLP-1 receptor agonists via the intestine, resulting in changes in insulin and glucose blood levels indicative of biopotencies of 9% for exendin-4 and 14.8% for semaglutide in preclinical models
Diabetes Care 45 , 23962405 (2022)
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10.1038/s41580-024-00703-5 36 DixonS