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When GLP-1 receptors in kidney tissue become activated, they can enhance sodium reabsorption in the collecting ductthe final filtering segment of the nephron

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Questo fondamentale nel trattamento del diabete di tipo 2, poich aiuta a controllare i picchi post-prandiali della glicemia senza causare ipoglicemia grave (cio una brusca diminuzione del glucosio nel sangue)