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For instance, building upon the established role of GPX4 in suppressing ferroptosis in alveolar cells, the demonstrated therapeutic potential of mesenchymal stem cell-derived exosomes, the feasibility of CD44-mediated macrophage targeting, and the precedent for pulmonary nucleic acid delivery, the engineering of inhaled exosomes to deliver GPX4 mRNA specifically to alveolar macrophages represents a promising frontier (175, 178)

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7% in the triple therapy arm ( p = 0.04)

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Some individuals may experience mild injection site sensitivity, temporary fatigue, or mild gastrointestinal sensitivity during the first one to two weeks of protocol adaptation all typically mild and temporary

Some pathological findings in the neuroglia and in the ganglion cells of the cortex in senile conditions