Additional studies demonstrated that SREBP-1c -/- mice had impaired induction of hepatic genes coding for fatty acid biosynthesis (e.g., acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase) compared to wild type mice [17]
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Besides, a novel GLP-1/GIP receptor agonist DA5-CH could reverse STZ-induced working memory and spatial memory impairments in rats (79)
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[Accessed April 2026] Gobburu JV, et al, Pharmacokinetic-pharmacodynamic modeling of ipamorelin in healthy volunteers, Journal of Clinical Pharmacology, 1999