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This finding is consistent with leading CKD treatment guidelines, where SGLT2is are recommended as first line in addition to RAS inhibition, metformin and statins [2, 7], and reflects the breadth of pivotal trial data (DAPA-CKD, EMPA-KIDNEY and CREDENCE) demonstrating earlier kidney and cardiovascular benefits (e.g

The difference is mainly in the dose of the medication thats used

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A clinical study involving healthy, non-fasting adults demonstrated that oral administration of -EC significantly increased lymphocyte GSH levels, indicating its systemic bioavailability 24

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