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In a similar model of LDLr-/- mice, alogliptin (30 mg/kg/d for 7 weeks) reduced the collagen-1 mRNA expression and triglyceride levels in hepatic cells

Hussein MR, Elsers DA, Fadel SA, Omar AE

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To assess the mitochondrial respiration rate, the cells were incubated in XF base medium (Agilent Technologies, Inc.) supplemented with 10 mM glucose, 1 mM pyruvate and 2 mM glutamine for 1.5 h at 37C