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Rubenstein & Merzenich, 2003) involving either or both upregulated glutamatergic excitatory and down-regulated GABAergic inhibitory systems(Sohal & Rubenstein, 2019)

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126 Taken together, current evidence suggests that metformin monotherapy in PCOS populations with infertility seems beneficial for ovulation and pregnancy in some subgroups, especially in treatmentnave women, but is less effective in CC or letrozoleresistant subgroups

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Endoplasmic reticulum (ER) stress is a secondary response caused by oxidative stress or inflammation mediated by aggregated proteins 14,15

Length describes how far the needle travels into tissue