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This can be due to weakening of the stomach lining (also known as atrophic gastritis), or to medications that reduce stomach acid

Ongoing trials Trials like NCT07328100 (intravenous coenzyme I for vascular aging, 2026 start) and NCT05243290 (oral NR in Gulf War Illness) continue to expand the human evidence base

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Thin (100 nm thick) sections were cut with a diamond knife on an Ultracut E ultramicrotome, collected onto 300 mesh copper grids and allowed to air dry