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This MOF nanosystem could react with GSH to generate Mn 2+ , TCPP, and GSSG, leading to decomposition of MOF

APR-017 treatment led to increased ROS level and decreased GSH level in PDCs with low expression of VRK2 rather than PDCs with high expression of VRK2 (Fig

Pergolide, known as Permax, is another ergot-derived agent available in oral form (55, 56)

DA-loaded exosomes were able to cross the BBB and were delivered to the striatum and SNpc, demonstrating enhanced therapeutic efficacy and reduced toxicity [291]