There is compelling evidence, including low plasma levels of GSH [12, 13], and effective antioxidant therapies (both with GSH [14] and its precursor, N-acetylcysteine [14, 15]), of REDOX imbalance contributing to the pathophysiology of several brain conditions such as obsessive-compulsive disorder, schizophrenia, bipolar disorder, autism, trichotillomania, and neurodegenerative disorders (see refs
[DOI] [Google Scholar] 27.Koibuchi N
Dwir D, Cabungcal J-H, Xin L, Giangreco B, Parietti E, Cleusix M, et al
Application of glutathione depletion in cancer therapy: enhanced ros-based therapy, ferroptosis, and chemotherapy
Additionally, the second aim of this study is to determine the levels of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) in resistant epilepsy patients who have not been studied before
A.LochnitG.BarretoG.GaluskaS