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Glucose production Glucose surge postprandial Glucagon-like peptide-1 (GLP-1) GLP-1 is a 30-amino-acid, incretin hormone secreted by intestinal L-cells in response to nutrient intake

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Liver X Receptor Agonists Augment Human Islet Function through Activation of Anaplerotic Pathways and Glycerolipid/Free Fatty Acid Cycling.J Biol Chem,2010;285(8): 5392-04

Enteroendocrine cells (EECs), specialized neuroendocrine cells of the intestinal epithelium, mediate this postprandial gut feedback, as they sense the luminal milieu and release gut peptides that influence metabolic homeostasis, such as GLP-1 and cholecystokinin (CCK) 16

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