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Akbarzadeh A, Rezaei-Sadabady R, Davaran S, Woo Joo S, Zarghami N, Hanifehpour Y, Samiei M, Kouhi M, Nejati-Koshki K

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6 The study showed that aspartate aminotransferase or alanine aminotransferase concentrations rose to above 1000 IU per liter in 6.1% of patients who were treated within 10 hours after ingestion and in 26.4% of those treated between 10 and 24 hours after ingestion

NNMT Inhibition Mechanism and Optimal Dosing Range 5-Amino-1MQ functions as a small-molecule competitive inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme responsible for methylating nicotinamide