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It is commonly used to treat type 2 diabetes but has also shown a significant efficacy for weight loss

Furthermore, certain chelators can disrupt iron-dependent neurophysiological processes, thereby further constraining their clinical applicability in NDDs (Marupudi and Xiong, 2024)

Unlike hormonal compounds, discontinuation simply means return to baseline rather than below-baseline function

Initial clinical trials appeared to validate the beneficial effect of incretins, specifically: A small open-label Phase 1 study (2013) with exenatide (Byetta, twice daily, beginning with 5 g/dose for a month and then increased to 10 g/dose) in 45 patients with PD of moderate severity

DOI.org (Crossref) , Veprikova, Zdenka, et al