41,42 Although humans can excrete small amounts of mercury in urine or feces as well as via exhalation or sweating, they lack an active robust mechanism for mercury excretion, allowing levels to accumulate with chronic exposure
Logistic issues: Extremely expensive (e.g., ~$25,000/treatment)
The developing fetus relies entirely on maternal B12 stores, which are actively transported across the placenta
Moreover, L-carnitine co-administration confers partial nephroprotection in mice treated with colistin, without interfering with its pharmacokinetics and antibacterial activity
Dumitrascu R, Heitmann J, Seeger W, Weissmann N, Schulz R (2013) Obstructive sleep apnea, oxidative stress and cardiovascular disease: lessons from animal studies
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