For the high dose group, most of the collagen was crimped seriously, the shape was irregular, and the arrangement was disordered
Initially, 6000 units of heparin sodium diluted in 3 ml of 0.9% saline were administered, followed by a nebulised mixture containing 2 mg of budesonide, 0.3 g of N-acetylcysteine, and 0.5 mg of ipratropium bromide, with a filling volume of 9 ml, after a five-minute interval
The procedure is fast, and any discomfort is generally mild and temporary
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To obtain crystals of the AsA-bound protein, Cys20-mutated OsDHAR (C20S) was used, which lacks reductase activity but exhibits AsA binding activity