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In the current study, majority of the lipofuscin-containing cells were hepatocytes (ASGR1 + ), supporting previous findings which showed that hepatocyte senescence facilitated liver pathogenesis 52,71

The trade-off researchers weigh is that more frequent stimulation of the ghrelin receptor could, in principle, blunt responsiveness over time a receptor-desensitization concern that is plausible but not well characterized for Ipamorelin specifically