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Is this injection safe for long-term use

Yes, but thats because they dont contain FDA-approved GLP-1 receptor agonist medications

Li et al., 2017)

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In the case of chronic hyponatremia, treatment is variable: when sodium is 120129 mEq/L and the patient is mildly symptomatic or asymptomatic, it is sufficient to discontinue any drugs potentially causing hyponatremia, manage the underlying cause of low sodium, and limit oral or intravenous intake of water

There's no single target because individual needs vary by metabolism, activity level, and starting weight