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135,158 Preclinical studies conducted on nematodes have reported that metformin treatment showed amelioration in neuronal function along with enhanced touch sensitivity in models of HD through activation of AMPK and the neuroprotective effect was abolished on blocking the effect of the gene AMPK1 (Figure 3)

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Calcif Tissue Int 110:576591 Jensen VFH, Mlck AM, Dalgaard M, McGuigan FE, Akesson KE (2021) Changes in bone mass associated with obesity and weight loss in humans: applicability of animal models

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Nutrients 10:E147 Keller TC, Gordon PV (1991) Discrete subcellular localization of a cytoplasmic and a mitochondrial isozyme of creatine kinase in intestinal epithelial cells