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Collectively, these clinical studies underscore the diverse therapeutic potential of natural compounds in addressing AD pathology and related symptoms

Despite promising preclinical data, challenges such as poor bioavailability, dose-dependent safety concerns, and the need for large-scale randomized clinical trials and regulatory standardization remain

During atherosclerosis regression, macrophage IDO1 knockdown obstructs responses that contribute to plaque-stabilizing characteristics

Protocol duration typically runs 8-16 weeks

The degree to which autophagy induction leads to observable enhancements in human metabolic health, especially among individuals with T2DM or metabolic syndrome, is still not fully understood [27]

Antioxidants-related superoxide dismutase ( SOD ), catalase ( cat ), glutathione peroxidase ( GPX ), glutathione-S-transferase ( gst ), and nitric oxide synthase ( NOS ) gene variants analysis in an obese population: A preliminary case-control study