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In its reduced state (GSH), glutathione serves to mediate oxidative stress and signaling by covalently scavenging various reactive species, such as hydrogen peroxide and superoxide, as a ubiquitous low-molecular-weight thiol [1]

619 In a randomized, placebo-controlled, crossover trial, 23 individuals with coronary artery disease received 200 mg pycnogenol daily for eight weeks followed by placebo for eight weeks, or vice versa

Brain: Besides the gut, the brain, particularly the nucleus of the solitary tract, also produces GLP-1, which functions as a neurotransmitter influencing a range of body processes, including appetite and energy balance

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The FASEB Journal, 20 (2), 377-379.

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