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Research Context Researchers study PT-141 to investigate MC3R/MC4R-selective melanocortin signaling in preclinical models

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80 L of each plasma sample is transferred to previously prepared tubes containing 240 L of ice-cold acetonitrile and vortexed vigorously

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Lawitz EJ, Fraessdorf M, Neff GW, Schattenberg JM, Noureddin M, Alkhouri N, Schmid B, Andrews CP, Takcs I, Hussain SA, Fenske WK, Gane EJ, Hosseini-Tabatabaei A, Sanyal AJ, Mazo DF, Younes R

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